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1. #COMPREHENSIVE META ANALYSIS SINGLE SUBJECT REGISTRATION#
2. #COMPREHENSIVE META ANALYSIS SINGLE SUBJECT SOFTWARE#
3. #COMPREHENSIVE META ANALYSIS SINGLE SUBJECT SERIES#

Temporomandibular joint disorder (TMD) is a general term for a series of diseases involving the temporomandibular joint, masticatory muscles, and surrounding structures.

#COMPREHENSIVE META ANALYSIS SINGLE SUBJECT REGISTRATION#

Protocol registration number: INPLASY202160030. However, the above conclusions need to be further verified by multicenter prospective studies of larger samples and higher-quality RCTs. This systematic review and meta-analysis provides new evidence for the effectiveness of WNA for the treatment of TMD. The data in this review showed that WNA is superior to treatments such as acupuncture alone, acupuncture therapy combined with TDP, drug therapy, and ultrasonic therapy in terms of effective rate (RR = 1.20 95% CI, 1.06 to 1.35 and P = 0.003) and cure rate (RR = 1.82 95% CI, 1.46 to 2.28 and P < 0.00001) for the treatment of TMD. The meta-analysis included 10 studies with a total of 670 patients, which included 340 patients in the experimental group and 330 patients in the control group. Measurement count data used the relative risk (RR) as the efficacy statistic, and each effect size was given its point estimate value and 95% confidence interval (CI).

#COMPREHENSIVE META ANALYSIS SINGLE SUBJECT SOFTWARE#

All analyses were conducted using RevMan software V5.3 and Stata16. And outcome indicators such as total effective rate and cure rate were assessed. The included RCTs compared WNA with acupuncture, electroacupuncture, pharmacological therapy, or other therapies. We searched randomized controlled trials (RCTs) of WNA for the treatment of TMD from 9 electronic databases, including 5 English databases (PubMed, EMBASE, Cochrane Library, Web of Science, and MEDLINE) and 4 Chinese databases (Chinese National Knowledge Infrastructure (CNKI), Chinese VIP Information, Wanfang Database, and Chinese Biomedical Literature Database (CBM)) from their inception to May 2021. This study aims to use a systematic review and meta-analysis method to understand the efficacy of WNA for the treatment of TMD.

However, evidence from evidence-based medicine is lacking. In recent years, there have been an increasing number of studies utilizing warm needle acupuncture (WNA) for the treatment of TMD, and the quality of the studies has gradually improved. Temporomandibular joint disorders (TMDs) are a common and prevalent disease with main symptoms of pain, joint sounds, and mandibular movement disorders, which seriously affects the mental health and quality of life of the sufferers.